Anthony Gesamondo was born on July 2, 1949 in Chelsea, Massachusetts, to a first generation Italian-American and a Registered Nurse of "typical" American heritage. He grew up in Revere, Massachusetts, where he attended Immaculate Conception School before graduating from the University of Massachusetts, Boston with a B.A. in English.

Anthony is a Vice-President at Great Northern Manufacturing. He is active in the Kiwanis Club and is the President of the Fund for Autistic Children.

From 1994 to 1998, Gesamondo was the Sports Editor for the Post-Gazette, the Italo-American newspaper for Eastern Massachusetts.

Anthony is married with three sons.